- The body changes over the years, and many people also take several medicines and have several conditions. That makes side effects more likely.
- When you are high, your reactions and attention are impaired. That can lead to falls and injuries.
- Talk to your GP about it, especially if you have heart disease or take medication regularly.
What changes with age
Older people have a particularly high risk of side effects from cannabis. Experts give these reasons: the physical changes that come with age, several medicines taken at the same time, their interactions and several illnesses at once. The body reacts more sensitively. With edibles, there is the added problem that the effect sets in slowly and with a delay. Anyone who takes more because they cannot feel anything yet risks an overdose.
What figures from North America show
In California, the number of cannabis-related emergency department visits among people aged 65 and over rose from 366 in 2005 to 12,167 in 2019. In Ontario, people aged 65 and over came to the emergency department with cannabis poisoning considerably more often after legalisation, most of all once edibles were allowed too. In about one in six of these cases, alcohol was also involved. The Deutsches Ärzteblatt sums up the study like this: older people apparently tend to choose edibles and often underestimate their effect. The figures cannot be transferred directly to Germany. But they show where the risks lie.
Falls and accidents
THC can slow down your reactions and disrupt your attention. That can lead to injuries and falls. One study found a higher risk of falling and a less steady gait in people aged 50 and over who use cannabis regularly. Further studies are still needed. What applies to driving is explained in the module Road traffic and the law.
Heart and circulation
Cannabis may be linked to a higher risk of heart attack, atrial fibrillation and heart failure. Studies show this association, but there is no proof that cannabis is the cause. In the first hour after smoking, THC can trigger heart rhythm problems. The American Heart Association advises against smoking or vaping anything, cannabis included. If you have heart disease, you will find more in the module Who should avoid cannabis.
Medication
THC and CBD slow down enzymes in the liver that break down many medicines. This can affect antidepressants, anticoagulants such as phenprocoumon, medicines for heart rhythm problems and medicines for high blood lipids, among others. With the anticoagulant clopidogrel, on the other hand, the effect can become weaker. The data mostly come from laboratory studies; studies in humans are often lacking. How strong the effect is in everyday life therefore remains unclear. That is exactly why the question belongs in the doctor’s surgery or the pharmacy.
Memory
A study from Ontario followed people aged 45 and over. Those who had been treated in an emergency department or in hospital for the effects of cannabis use were diagnosed with dementia more often in the following years than people of the same age. The researchers stress that this is an association, not proof that cannabis is the cause.
Talking to your GP
Tell your GP openly whether and how you use cannabis. Doctors are bound by medical confidentiality. Anyone who takes at least three prescribed medicines at the same time is entitled to a medication plan. How to prepare for the appointment is explained in the checklist for talking to your doctor.
If you take cannabis or want to take it for pain or sleep problems, discuss it with a doctor. Cannabis as a medicine is regulated by the Medical Cannabis Act and is prescribed by doctors.
Sources
- Stall et al., “Edible Cannabis Legalization and Cannabis Poisonings in Older Adults”, JAMA Internal Medicine 2024 (people aged 65 and over, Ontario 2015 to 2022, alcohol in 16.6 %; reasons for vulnerability)
- Deutsches Ärzteblatt, rise in cannabis poisonings among older people, 23 May 2024 (freely readable teaser)
- UC San Diego Health, “Cannabis-Related Emergency Department Visits among Older Adults on the Rise”, 9 January 2023
- Rudroff, “Cannabis Use and Risk of Falling in Older Adults”, Innovation in Aging 2022 (conference paper)
- American Heart Association, scientific statement on cannabis and cardiovascular health, 5 August 2020
- Pharmazeutische Zeitung, cannabis as an interaction partner, 19 January 2022
- Myran, Pugliese, Harrison, Stall, Webber, “Risk of Dementia in Individuals With Emergency Department Visits or Hospitalizations Due to Cannabis”, JAMA Neurology 2025 (people aged 45 to 105, Ontario; “should not be interpreted as causal”)
- BIÖG, information sheet on cannabis for members of cultivation associations, as of February 2025 (edibles: delayed effect)
- § 31a SGB V (medication plan)
- Federal Ministry of Health, FAQ on the Cannabis Act (medical cannabis), as of 4 September 2026